CovidSeniorV1, Main, Exploration, bibRecord, 000239

ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.

Identifieur interne : 000239 ( Main/Exploration ); précédent : 000238; suivant : 000240

ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.

Auteurs : Mario Gramegna [Italie] ; Luca Baldetti [Italie] ; Alessandro Beneduce [Italie] ; Luigi Pannone [Italie] ; Giulio Falasconi [Italie] ; Francesco Calvo [Italie] ; Vittorio Pazzanese [Italie] ; Stefania Sacchi [Italie] ; Matteo Pagnesi [Italie] ; Francesco Moroni [Italie] ; Silvia Ajello [Italie] ; Giulio Melisurgo [Italie] ; Eustachio Agricola [Italie] ; Paolo G. Camici ; Anna Mara Scandroglio [Italie] ; Giovanni Landoni [Italie] ; Fabio Ciceri [Italie] ; Alberto Zangrillo [Italie] ; Alberto Maria Cappelletti [Italie]

Source :

Circulation. Cardiovascular interventions [ 1941-7632 ] ; 2020.

RBID : pubmed:32791953

Descripteurs français

KwdFr :
- Adulte d'âge moyen (MeSH), Betacoronavirus (MeSH), Enregistrements (MeSH), Femelle (MeSH), Humains (MeSH), Infarctus du myocarde avec sus-décalage du segment ST (chirurgie), Infarctus du myocarde avec sus-décalage du segment ST (complications), Infections à coronavirus (complications), Infections à coronavirus (épidémiologie), Intervention coronarienne percutanée (méthodes), Italie (épidémiologie), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (complications), Pneumopathie virale (épidémiologie), Pratiques en santé publique (MeSH), Sujet âgé (MeSH), Études prospectives (MeSH).
MESH :
- chirurgie : Infarctus du myocarde avec sus-décalage du segment ST.
- méthodes : Intervention coronarienne percutanée.
- épidémiologie : Infarctus du myocarde avec sus-décalage du segment ST, Infections à coronavirus, Italie, Pneumopathie virale.
- Adulte d'âge moyen, Betacoronavirus, Enregistrements, Femelle, Humains, Mâle, Pandémies, Pratiques en santé publique, Sujet âgé, Études prospectives.
Wicri :
- geographic : Italie.

English descriptors

KwdEn :
- Aged (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (complications), Coronavirus Infections (epidemiology), Female (MeSH), Humans (MeSH), Italy (epidemiology), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Percutaneous Coronary Intervention (methods), Pneumonia, Viral (complications), Pneumonia, Viral (epidemiology), Prospective Studies (MeSH), Public Health Practice (MeSH), Registries (MeSH), ST Elevation Myocardial Infarction (complications), ST Elevation Myocardial Infarction (surgery).
MESH :
- geographic , epidemiology : Italy.
- complications : Coronavirus Infections, Pneumonia, Viral, ST Elevation Myocardial Infarction.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- methods : Percutaneous Coronary Intervention.
- surgery : ST Elevation Myocardial Infarction.
- Aged, Betacoronavirus, Female, Humans, Male, Middle Aged, Pandemics, Prospective Studies, Public Health Practice, Registries.

Abstract

BACKGROUND

Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.

METHODS

This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.

RESULTS

A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours;

CONCLUSIONS

These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.

DOI: 10.1161/CIRCINTERVENTIONS.120.009413
PubMed: 32791953

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000666
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Le document en format XML

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<author><name sortKey="Cappelletti, Alberto Maria" sort="Cappelletti, Alberto Maria" uniqKey="Cappelletti A" first="Alberto Maria" last="Cappelletti">Alberto Maria Cappelletti</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.</title>
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<author><name sortKey="Baldetti, Luca" sort="Baldetti, Luca" uniqKey="Baldetti L" first="Luca" last="Baldetti">Luca Baldetti</name>
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<author><name sortKey="Pannone, Luigi" sort="Pannone, Luigi" uniqKey="Pannone L" first="Luigi" last="Pannone">Luigi Pannone</name>
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<author><name sortKey="Falasconi, Giulio" sort="Falasconi, Giulio" uniqKey="Falasconi G" first="Giulio" last="Falasconi">Giulio Falasconi</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Calvo, Francesco" sort="Calvo, Francesco" uniqKey="Calvo F" first="Francesco" last="Calvo">Francesco Calvo</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pazzanese, Vittorio" sort="Pazzanese, Vittorio" uniqKey="Pazzanese V" first="Vittorio" last="Pazzanese">Vittorio Pazzanese</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sacchi, Stefania" sort="Sacchi, Stefania" uniqKey="Sacchi S" first="Stefania" last="Sacchi">Stefania Sacchi</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pagnesi, Matteo" sort="Pagnesi, Matteo" uniqKey="Pagnesi M" first="Matteo" last="Pagnesi">Matteo Pagnesi</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moroni, Francesco" sort="Moroni, Francesco" uniqKey="Moroni F" first="Francesco" last="Moroni">Francesco Moroni</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ajello, Silvia" sort="Ajello, Silvia" uniqKey="Ajello S" first="Silvia" last="Ajello">Silvia Ajello</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Melisurgo, Giulio" sort="Melisurgo, Giulio" uniqKey="Melisurgo G" first="Giulio" last="Melisurgo">Giulio Melisurgo</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Agricola, Eustachio" sort="Agricola, Eustachio" uniqKey="Agricola E" first="Eustachio" last="Agricola">Eustachio Agricola</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Imaging Unit (E.A.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Imaging Unit (E.A.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
<affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation>
<wicri:noCountry code="subField">A.Z.).</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Camici, Paolo G" sort="Camici, Paolo G" uniqKey="Camici P" first="Paolo G" last="Camici">Paolo G. Camici</name>
<affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation>
<wicri:noCountry code="subField">A.Z.).</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Scandroglio, Anna Mara" sort="Scandroglio, Anna Mara" uniqKey="Scandroglio A" first="Anna Mara" last="Scandroglio">Anna Mara Scandroglio</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name>
<affiliation wicri:level="3"><nlm:affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
<affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation>
<wicri:noCountry code="subField">A.Z.).</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ciceri, Fabio" sort="Ciceri, Fabio" uniqKey="Ciceri F" first="Fabio" last="Ciceri">Fabio Ciceri</name>
<affiliation wicri:level="3"><nlm:affiliation>Hematology Department (F. Ciceri), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Hematology Department (F. Ciceri), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
<affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation>
<wicri:noCountry code="subField">A.Z.).</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zangrillo, Alberto" sort="Zangrillo, Alberto" uniqKey="Zangrillo A" first="Alberto" last="Zangrillo">Alberto Zangrillo</name>
<affiliation wicri:level="3"><nlm:affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
<affiliation><nlm:affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</nlm:affiliation>
<wicri:noCountry code="subField">A.Z.).</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cappelletti, Alberto Maria" sort="Cappelletti, Alberto Maria" uniqKey="Cappelletti A" first="Alberto Maria" last="Cappelletti">Alberto Maria Cappelletti</name>
<affiliation wicri:level="3"><nlm:affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Circulation. Cardiovascular interventions</title>
<idno type="eISSN">1941-7632</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Coronavirus Infections (complications)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Italy (epidemiology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Percutaneous Coronary Intervention (methods)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Prospective Studies (MeSH)</term>
<term>Public Health Practice (MeSH)</term>
<term>Registries (MeSH)</term>
<term>ST Elevation Myocardial Infarction (complications)</term>
<term>ST Elevation Myocardial Infarction (surgery)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Enregistrements (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infarctus du myocarde avec sus-décalage du segment ST (chirurgie)</term>
<term>Infarctus du myocarde avec sus-décalage du segment ST (complications)</term>
<term>Infections à coronavirus (complications)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Intervention coronarienne percutanée (méthodes)</term>
<term>Italie (épidémiologie)</term>
<term>Mâle (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (complications)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Pratiques en santé publique (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Études prospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Italy</term>
</keywords>
<keywords scheme="MESH" qualifier="chirurgie" xml:lang="fr"><term>Infarctus du myocarde avec sus-décalage du segment ST</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>ST Elevation Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Percutaneous Coronary Intervention</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Intervention coronarienne percutanée</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>ST Elevation Myocardial Infarction</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infarctus du myocarde avec sus-décalage du segment ST</term>
<term>Infections à coronavirus</term>
<term>Italie</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Betacoronavirus</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Prospective Studies</term>
<term>Public Health Practice</term>
<term>Registries</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Betacoronavirus</term>
<term>Enregistrements</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Pratiques en santé publique</term>
<term>Sujet âgé</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Italie</term>
</keywords>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours; </p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32791953</PMID>
<DateCompleted><Year>2020</Year>
<Month>08</Month>
<Day>27</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>08</Month>
<Day>27</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1941-7632</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>13</Volume>
<Issue>8</Issue>
<PubDate><Year>2020</Year>
<Month>08</Month>
</PubDate>
</JournalIssue>
<Title>Circulation. Cardiovascular interventions</Title>
<ISOAbbreviation>Circ Cardiovasc Interv</ISOAbbreviation>
</Journal>
<ArticleTitle>ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.</ArticleTitle>
<Pagination><MedlinePgn>e009413</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1161/CIRCINTERVENTIONS.120.009413</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.</AbstractText>
<AbstractText Label="METHODS">This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.</AbstractText>
<AbstractText Label="RESULTS">A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours; <i>P</i>
<0.01). A higher proportion of patients presenting with late presentation STEMI was observed in 2020 compared with the historical cohort (50.0% versus 4.8%; <i>P</i>
<0.01). Primary percutaneous coronary intervention resulted indicated in 80.8% of patients in 2020 compared with 100% in the historical cohort (<i>P</i>
=0.06). In-hospital death, thromboembolism, mechanical ventilation, or hemodynamic decompensation needing inotropic or mechanical support were similar between years.</AbstractText>
<AbstractText Label="CONCLUSIONS">These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gramegna</LastName>
<ForeName>Mario</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baldetti</LastName>
<ForeName>Luca</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Beneduce</LastName>
<ForeName>Alessandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Interventional Cardiology Unit (A.B.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pannone</LastName>
<ForeName>Luigi</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Falasconi</LastName>
<ForeName>Giulio</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Calvo</LastName>
<ForeName>Francesco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pazzanese</LastName>
<ForeName>Vittorio</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sacchi</LastName>
<ForeName>Stefania</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pagnesi</LastName>
<ForeName>Matteo</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moroni</LastName>
<ForeName>Francesco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ajello</LastName>
<ForeName>Silvia</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Melisurgo</LastName>
<ForeName>Giulio</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Agricola</LastName>
<ForeName>Eustachio</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Cardiac Imaging Unit (E.A.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Camici</LastName>
<ForeName>Paolo G</ForeName>
<Initials>PG</Initials>
<AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Scandroglio</LastName>
<ForeName>Anna Mara</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Cardiac Surgery Intensive Care Unit (S.A., G.M., A.M.S.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Landoni</LastName>
<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ciceri</LastName>
<ForeName>Fabio</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Hematology Department (F. Ciceri), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zangrillo</LastName>
<ForeName>Alberto</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Anesthesia and Intensive Care (G.L., A.Z.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Vita-Salute San Raffaele University, Milan, Italy (E.A., P.G.C., G.L., F. Ciceri, A.Z.).</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cappelletti</LastName>
<ForeName>Alberto Maria</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Cardiac Intensive Care Unit (M.G., L.B., L.P., G.F., F. Calvo, V.P., S.S., M.P., F.M., A.M.C.), IRCCS San Raffaele Scientific Institute, Milan, Italy.</Affiliation>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>08</Month>
<Day>14</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Circ Cardiovasc Interv</MedlineTA>
<NlmUniqueID>101499602</NlmUniqueID>
<ISSNLinking>1941-7640</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007558" MajorTopicYN="N" Type="Geographic">Italy</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D062645" MajorTopicYN="N">Percutaneous Coronary Intervention</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015980" MajorTopicYN="Y">Public Health Practice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012042" MajorTopicYN="Y">Registries</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000072657" MajorTopicYN="N">ST Elevation Myocardial Infarction</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">acute coronary syndrome</Keyword>
<Keyword MajorTopicYN="Y">coronavirus</Keyword>
<Keyword MajorTopicYN="Y">myocardial infarction</Keyword>
<Keyword MajorTopicYN="Y">pandemic</Keyword>
<Keyword MajorTopicYN="Y">severe acute respiratory syndrome coronavirus 2</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>8</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>8</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>8</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32791953</ArticleId>
<ArticleId IdType="doi">10.1161/CIRCINTERVENTIONS.120.009413</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Italie</li>
</country>
<region><li>Lombardie</li>
</region>
<settlement><li>Milan</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Camici, Paolo G" sort="Camici, Paolo G" uniqKey="Camici P" first="Paolo G" last="Camici">Paolo G. Camici</name>
</noCountry>
<country name="Italie"><region name="Lombardie"><name sortKey="Gramegna, Mario" sort="Gramegna, Mario" uniqKey="Gramegna M" first="Mario" last="Gramegna">Mario Gramegna</name>
</region>
<name sortKey="Agricola, Eustachio" sort="Agricola, Eustachio" uniqKey="Agricola E" first="Eustachio" last="Agricola">Eustachio Agricola</name>
<name sortKey="Ajello, Silvia" sort="Ajello, Silvia" uniqKey="Ajello S" first="Silvia" last="Ajello">Silvia Ajello</name>
<name sortKey="Baldetti, Luca" sort="Baldetti, Luca" uniqKey="Baldetti L" first="Luca" last="Baldetti">Luca Baldetti</name>
<name sortKey="Beneduce, Alessandro" sort="Beneduce, Alessandro" uniqKey="Beneduce A" first="Alessandro" last="Beneduce">Alessandro Beneduce</name>
<name sortKey="Calvo, Francesco" sort="Calvo, Francesco" uniqKey="Calvo F" first="Francesco" last="Calvo">Francesco Calvo</name>
<name sortKey="Cappelletti, Alberto Maria" sort="Cappelletti, Alberto Maria" uniqKey="Cappelletti A" first="Alberto Maria" last="Cappelletti">Alberto Maria Cappelletti</name>
<name sortKey="Ciceri, Fabio" sort="Ciceri, Fabio" uniqKey="Ciceri F" first="Fabio" last="Ciceri">Fabio Ciceri</name>
<name sortKey="Falasconi, Giulio" sort="Falasconi, Giulio" uniqKey="Falasconi G" first="Giulio" last="Falasconi">Giulio Falasconi</name>
<name sortKey="Landoni, Giovanni" sort="Landoni, Giovanni" uniqKey="Landoni G" first="Giovanni" last="Landoni">Giovanni Landoni</name>
<name sortKey="Melisurgo, Giulio" sort="Melisurgo, Giulio" uniqKey="Melisurgo G" first="Giulio" last="Melisurgo">Giulio Melisurgo</name>
<name sortKey="Moroni, Francesco" sort="Moroni, Francesco" uniqKey="Moroni F" first="Francesco" last="Moroni">Francesco Moroni</name>
<name sortKey="Pagnesi, Matteo" sort="Pagnesi, Matteo" uniqKey="Pagnesi M" first="Matteo" last="Pagnesi">Matteo Pagnesi</name>
<name sortKey="Pannone, Luigi" sort="Pannone, Luigi" uniqKey="Pannone L" first="Luigi" last="Pannone">Luigi Pannone</name>
<name sortKey="Pazzanese, Vittorio" sort="Pazzanese, Vittorio" uniqKey="Pazzanese V" first="Vittorio" last="Pazzanese">Vittorio Pazzanese</name>
<name sortKey="Sacchi, Stefania" sort="Sacchi, Stefania" uniqKey="Sacchi S" first="Stefania" last="Sacchi">Stefania Sacchi</name>
<name sortKey="Scandroglio, Anna Mara" sort="Scandroglio, Anna Mara" uniqKey="Scandroglio A" first="Anna Mara" last="Scandroglio">Anna Mara Scandroglio</name>
<name sortKey="Zangrillo, Alberto" sort="Zangrillo, Alberto" uniqKey="Zangrillo A" first="Alberto" last="Zangrillo">Alberto Zangrillo</name>
</country>
</tree>
</affiliations>
</record>

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   |wiki=    Sante
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   |clé=     pubmed:32791953
   |texte=   ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.
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ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.

ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub.

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